Are you using the debug version of extjs lib? (ex: ext-all-debug). Firebug does have a callstack to where you can see what triggered the call. Can you set a break point where you suspect things are going wrong?
I'd set a breakpoint if I knew where the prob was. I'm not keen on blind willynillyness, id prefer to be told the exact point the code is failing not some generic apply call.
The stack ends at some closure that means nothing to me.
I have since found where the prob is, in the onRender method of a Container I've extended - nowhere in the trace (AFAIK) was this mentioned.
This is my point in question...ever since I've gone with Ext JS I've lost many hours to this exact problem.