My application was working fine with ST 2.1.0 but after upgrading to ST 2.2.0, it's not working properly on iOS 4.3.3.
After loading and rendering the UI, the app doesn't response to touch event.
Tap on buttons, list items doesn't work anymore.

The same problem with Sencha Touch Demo Apps in version 2.2.0.
Open below link on my iPod Touch to view GeoCongress app
http://docs.sencha.com/touch/2.2.0/t...ess/index.html

I'm using iPod Touch device for testing, you can see my device userAgent below
"Mozilla/5.0 (iPod; U; CPU iPhone OS 4_3_3 like Mac OS X; en-us) AppleWebKit/533.17.9 (KHTML, like Gecko) Mobile/8J2"

After spending two days to debug and troubleshot, I found the root cause of this bug.
It's because of the changes on Ext.event.publisher.Dom, see below diffs.
Code:
 
-    attachListener: function(eventName) {
-        document.addEventListener(eventName, this.onEvent, !this.doesEventBubble(eventName));
+    bindListeners: function (doc, bind) {
+        var handlesEvents = this.getHandledEvents(),
+            handlesEventsLength = handlesEvents.length,
+            i;
+
+        for (i = 0; i < handlesEventsLength; i++) {
+            this.bindListener(doc, this.getVendorEventName(handlesEvents[i]), bind);
+        }
+    },
+
+    bindListener: function (doc, eventName, bind) {
+        if (bind) {
+            this.attachListener(eventName, doc);
+        } else {
+            this.removeListener(eventName, doc);
+        }
+        return this
+    },
+
+    attachListener: function(eventName, doc) {
+        if (!doc) {
+            doc = document;
+        }
+
+        var defaultView = doc.defaultView,
+            addEventListener;
 
+        if (defaultView && defaultView.addEventListener) {
+            addEventListener = defaultView.addEventListener;
+        }
+        else {
+            addEventListener = doc.addEventListener;
+        }
+        addEventListener(eventName, this.onEvent, !this.doesEventBubble(eventName));
         return this;
     },
Somehow, document.defaultView.addEventListener doesn't work as expected on iOS 4.3.3 with touchstart event so application won't be able to get any touch event from browser.
If I remove the new changes in attachListener method and use the old code in 2.1.0, everything is working fine again
Code:
document.addEventListener(eventName, this.onEvent, !this.doesEventBubble(eventName));
If you need a quick work around solution, then add this line of code to the top of your application (app.js)
Code:
document.addEventListener('touchstart', function(){}, false);
or
Code:
ocument.ontouchstart=function(){};